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Amphidinin B, a New Polyketide Metabolite from Marine Dinoflagellate Amphidinium sp.

Takaaki Kubota, Tetsuya Endo, Yohei Takahashi, Masashi Tsuda, Jun’ichi Kobayashi

This paper is dedicated to the memory of Professor Kenneth L. Rinehart at University of Illinois.

Received: June 1, 2006 / Accepted: August 10, 2006
© Japan Antibiotics Research Association

Abstract A new polyketide metabolite, amphidinin B (1), has been isolated from a marine dinoflagellate Amphidinium sp. and the structure and absolute stereochemistry were elucidated on the basis of spectroscopic data and chemical means.

Keywords amphidinin B, dinoflagellate, polyketide


J. Kobayashi (Corresponding author), T. Kubota, T. Endo, Y. Takahashi, M. Tsuda: Graduate School of Pharmaceutical Sciences Hokkaido University, Sapporo 060-0812, Japan,
E-mail: jkobay@pharm.hokudai.ac.jp