Received: June 1, 2006 / Accepted: August 16, 2006
© Japan Antibiotics Research Association
Abstract Cultures of a fungicolous isolate of Sporormiella minimoides afforded two new polyketide metabolites which we have named sporminarins A (1) and B (2). The planar structures of 1 and 2 were elucidated by analysis of NMR and MS data, and by chemical methods. 1 exhibited significant antifungal activity against Aspergillus flavus.
Keywords sporminarins, antifungal, Sporormiella minimoides
J. B. Gloer (Corresponding author), S. V. Mudur: Department of Chemistry, University of Iowa, Iowa City, Iowa 52242,
D. T. Wicklow: Mycotoxin and Crop Bioprotection Research Units, Agricultural Research Service, National Center for Agricultural Utilization Research, USDA, Peoria, Illinois 61604