ORIGINAL ARTICLE  

Yaequinolones, New Insecticidal Antibiotics Produced by Penicillium sp. FKI-2140

II. Structural Elucidation

Ryuji Uchida, Rie Imasato, Hiroshi Tomoda, Satoshi O_long.gif"mura

Received: June 29, 2006 / Accepted: October 9, 2006
© Japan Antibiotics Research Association

Abstract The structure and relative stereochemistry of yaequinolones, fungal insecticidal antibiotics, were elucidated by spectroscopic studies, including NMR spectral analyses. Yaequinolones possess a p-methoxyphenylquinolinone skeleton modified with different isoprenyl-derived side chains.

Keywords yaequinolone, insecticide, fungal metabolites, structural elucidation, Penicillium sp., p-methoxyphenylquinolinone


H. Tomoda (Corresponding author), R. Uchida: School of Pharmacy, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan, E-mail: tomodah@pharm.kitasato-u.ac.jp
R. Imasato, S. O_long.gif"mura: Kitasato Institute for Life Sciences, & Graduate School of Infection Control Sciences, Kitasato University and The Kitasato Institute, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan